2nd Annual New England Protein Science Forum
New Techniques in Protein Sciences - developments in protein science for biopharma and drug discovery

Bentley University
Waltham, MA 
Friday, November 7, 2008

Schedule:

8:00 am Check-in and light breakfast
9:00 - 9:10 am Introduction
Rajiv Chopra, NESBA
Session I — Overcoming Challenges in Protein Expression & Purification
(Session chair: Ian Hunt)
9:10 - 9:45 am Overcoming the challenges in supplying proteins for drug discovery; tricks and lessons learned in producing difficult to express proteins
Xin Huang, Amgen, Cambridge, MA
9:45 - 10:20 am E.coli and Baculovirus generated proteins for structure based drug design
James M. Groarke, Protein Structure Group, Novartis Institute for Biomedical Research, Cambridge, MA
10:20 - 10:55 am PER.C6® a Human Cell Line Expression platform
Blanca Lain, PERCIVIA, LLC, Cambridge, MA
10:55 - 11:10 am Coffee Break and Posters Session
Session II — Advances in protein analytics & expression technologies
(Session chair: Ted Fox)
11:10 - 11:45 am Proteomics—Discovery and Translation of Biomarkers for Early Clinical Development
Cloud Paweletz, Molecular Profiling Proteomics, Merck Research Laboratories, Boston, MA
11:45 - 12:20 pm Analytical Untracentrifugation Applied to Drug Discovery and Development
John Doran, Vertex, Cambridge, MA
12:20 - 1:00 pm Lunch

Session IIIA — Biologics & Vaccines: Current trends and developments
(Session chair: Simon Low)
1:00 - 2:00 pm Keynote Speaker:
Stapled Peptides: A New Therapeutic Modality
Tomi Sawyer, Aileron Therapeutics, Cambridge, MA
2:00 - 2:35 pm Adnectins: Novel Targeted Biologics
Jochem Gokemeijer, Adnexus, Waltham, MA
2:35 - 2:50 pm Break and Posters Session
Session IIIB — Biologics & Vaccines: Current trends and developments
(Session chair: Stephen Chambers)
2:50 - 3:25 pm From Gene to a Marketed Biologic: An Overview of the Process and Points to Consider
Darren Baker, Biogen Idec, Cambridge, MA
3:25 - 4:00 pm

Production, Biochemical, Biophysical, and Immunological Characterization of Vaccines
Indresh Srivastava, Novartis Vaccines, Cambridge, MA

4:00 - 4:35 pm

Biological Therapeutics by Design Using Engineered Heterodimeric Fc Domains
Jonathan Davis, Adnexus, Waltham, MA

4:35 pm onwards Mixer and Posters Session

Meeting Sponsors:

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