NESBA CryoEM Symposium

NESBA half-day cryoEM symposium focused on Structure Based Drug Discovery and Current Methodology

New England Structural Biology Association is hosting a mini-symposium on October 3, 2024

The event will be hosted by Sanofi at Cambridge Crossing and is co-organized and sponsored by Nanoimaging Services with additional sponsorships from Refeyn and Clovertex.

Seats will be limited and the audience are scientists who have interest in the day-to-day working of cryoEM data processing, computational structure determination and the rational design of drugs using molecular structures.

Agenda

1:30 PM - 2.00 PMSanofi Structural Biology Team (30 minutes)
2:00 PM - 2:30 PMStructural Optimization for Enhanced TFR Targeted Brain Delivery: Joe Arndt, Biogen (30 minutes)
2:30 PM - 2:50 PMDesigning proteasome inhibitors by studying the structure of the endogenous inhibitor PI31/Fub1: Richard Walsh, Harvard Cryo-EM Center for Structural Biology (20 minutes)
2:50 PM - 3:20 PMStructural Virology by cryo-EM: from basic science to translation: Priyamvada Acharya, Duke Center for HIV Structural Biology at Duke University (30 minutes)
3:20 PM - 3:50 PMBreak (30 minutes)
3:50 PM - 4:10 PMUnderstanding the Mechanism of Action with Various Modalities for SBDD: Kevin Huynh, Pfizer (20 minutes)
4:10 PM - 4:30 PMStructure of anellovirus-like particles reveal a mechanism for immune evasion: Rajendra Boggavarapu, Ring Therapeutics (20 minutes)
4:30 PM - 4:50 PMSink or swim: using cryoEM to understand off-target hERG binding in Drug Discovery: Christine Carbone, Relay Therapeutics (20 minutes)
4:50 PM - 5:10 PMTowards rapid, purification-free structural biology (of ribosomes): Mira May, Massachusetts Institute of Technology (20 minutes)
5:10 PM - 5:30 PMSingle particle cryoEM in drug development targeting GPCRs: Ximena Barros-Álvarez, Tectonic Therapeutic (20 minutes)

Registration is now closed

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 Thursday, October 3, 2024
Time: 1:30 to 5:30 PM

Meeting location

Sanofi
450 Water Street
Cambridge, MA 02143

Mixer

5:30 - 8:00 PM
Geppetto
100 N First Street
Cambridge, MA 02141

 

 

The New England Structural Biology Association (NESBA) is a non-profit organization, run by volunteers. We are dedicated to bringing together industrial scientists with the shared vision of using protein structure to enable the design of novel therapeutics. NESBA disciplines include: Protein Sciences; X-ray Crystallography; NMR; Molecular Modeling; Biology; Chemistry; Computational Chemistry; and Electron Microscopy.

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