First Annual Meeting
Systems Biology in Drug Discovery

Bentley University
Waltham, MA 
October 5, 2006

Keynote Speakers:

Dr. Peter Sorger, Prof. of Biological Engineering, MIT
Dr. James Collins, Prof. of Biomedical Engineering, Boston University
and speakers from Cell Signaling Technology, Broad Institute, Genstruct, GE Global Research Center, BG Medicine, Stanford University

Panel discussion:

Integrating modeling into drug discovery
with representatives from Pfizer, Astra-Zeneca, Sanofi-Aventis, Novartis and Vertex


7:30 am Registration and light breakfast
8:15 am Opening remarks
Brian Hare
8:30 am Keynote Speaker: "Harnessing gene networks in drug discovery"
Dr. James Collins, Boston University
9:30 am "Identification of activated tyrosine kinases in human cancer using PhosphoScan® technology"
Dr. Roberto Polakiewicz, Cell Signaling Technology
10:00 am "Gene expression based high throughput screening and its application to cancer"
Dr. Ken Ross, Broad Institute
10:30 am "A systems biology approach for understanding of mechanisms of drug-induced vascular injury"
Dr. Keith Elliston, Genstruct
11:00 am Break
11:15 am Panel discussion:
Integrating Modeling into Drug Discovery

Moderator: Carolyn Cho

Dr. David de Graaf, Pfizer
Dr. Alan Buckler, Novartis
Dr. Mike Briggs, Vertex
Dr. Jack Beusmans, AstraZeneca R&D Boston
Dr. Jack Pollard, Sanofi-Aventis
12:30 pm Lunch
1:30 pm "Integrating modeling into imaging agent development"
Dr. Brion Sarachan, Global Research Center
2:00 pm "Integrated correlation networks for systems pathology & systems pharmacology"
Dr. Tom Plasterer, BG Medicine
2:30 pm "Human cell systems biology for chemical genomics and drug discovery: taking advantage of complexity in cellular models of disease"
Dr. Eugene Butcher, Stanford University
3:00 pm Keynote Speaker: "Systems pharmacology and anti-cancer therapy"
Dr. Peter Sorger, MIT

Meeting Sponsors:

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